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NEW ORLEANS - Vitamins C and E — pills captivated close millions of Americans — do nothing to anticipate Colloq ticker sickness in men, single of the largest and longest studies of these supplements has establish.
Vitamin E regular appeared to lift the danger of bleeding strokes, a danger seen in at least lone earlier learn.
Besides questioning whether vitamins aid, "we be obsessed or in ownership of to be anxious circular possible damage," said Barbara Howard, a nutrition scientist at MedStar Research Institute of Hyattsville, Md.
She has no rõle in the investigation but reviewed and discussed it Sunday at an American Heart Association appointment. Results also were published online beside the Journal of the American Medical Association.
About 12 percent of Americans grip supplements of C and E despite growing evidence that these antioxidants do not preclude send affliction and may even be dangerous.
Male smokers attractive vitamin E had a higher measure of bleeding strokes in a former read, and some others create no advantage representing heart condition.
As championing vitamin C, some investigating suggests it may assist cancer, not contend it. A former con in women at high peril of heart problems fellowship it did not obviate heart attacks.
Few extensive-name studies own been done. The new lone is the Physicians Health Study, led next to Drs. Howard Sesso and J. Michael Gaziano of Harvard-associated Brigham and Women's Hospital in Boston.
It implicated 14,641 masculine doctors, 50 or older, including 5 percent who had heart ailment at the period the memorize started in 1997. They were place into four groups and stated either vitamin E, vitamin C, both, or mannequin pills. The section of E was 400 supranational units every other daytime; C was 500 milligrams daily.
After an intend of eight years, no differentiation was seen in the rates of heart assail, blow or heart-associate deaths amongst the groups.
However, 39 men alluring E suffered bleeding strokes versus lone 23 of the others, which works exterior to a 74 percent greater jeopardy for vitamin-takers.
The burn the midnight oil was funded close to the National Institutes of Health and a few vitamin makers. Results were so unclouded that they would be improbable to exchange if the lucubrate were done in women, minorities, or with different formulations of the vitamins, Howard said.
"In these firm pecuniary times, maybe we can rescue some currency alongside not buying these supplements," she said.
A succeeding study place down up that vitamins B-12 and B-9 (folic acid) did not forestall heart malady either, supporting the results of past trials. That study concerned more than 12,000 heart assault survivors and was led by Dr. Jane Armitage of the University of Oxford in England.
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On the Net:
JAMA: http://jama.ama-assn.org/
Heart engagement: http://www.americanheart.org/